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Home > Part 2: General methods for Cochrane reviews > 9 Analysing data and undertaking meta-analyses > 9.6 Investigating heterogeneity > 9.6.3 UndertakingFirst, sensitivity analyses do not attempt to estimate the effect of the intervention in the group of studies removed from the analysis, whereas in subgroup Cochrane Handbook for Systematic Reviews of Interventions version 6.3 Heterogeneity may be explored by conducting subgroup analyses (see Section This is an archived version of the Handbook. For the current version, please go to training.cochrane.org/handbook/current or search for this chapter here. Subgroup analyses may be undertaken within RevMan. Meta-analyses within subgroups and meta-analyses that combine several subgroups are both permitted. 9.6.5.1 Ensure that there are adequate studies to justify subgroup analyses and meta-regressions. It is very unlikely that an investigation of heterogeneity Subgroup analyses involve splitting all the participant data into subgroups, often so as to make comparisons between them. Subgroup analyses may be done for It must be remembered that subgroup analyses and meta-regressions are entirely observational in their nature. These analyses investigate differences between
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