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The mechanism of action of probiotics (e.g., having an impact on the intestinal microbiota or enhancing immune function) was dropped from the definition to encompass health effects due to novel mechanisms and to allow application of the term before the mechanism is confirmed. Physiologic benefits have been attributed to dead microorganisms [ 1 ]. Historically, the development of probiotics was very much oriented toward pharmaceutical applications such as treatment of diarrhea, prevention of antibiotic-associated diarrhea, management of stomach and gastro-intestinal infections, management of chronic inflammation, and so on. Abstract. Probiotics constitute beneficial microorganisms or their components reported for their health benefits to the hosts. A plethora of research conducted over the past three decades resulted in elucidating the association of probiotic strains under different clinical manifestations. The relation of Probiotics to our health could be summarized in the following main points and facts: 1. Probiotics are helpful formed of friendly microorganisms. 2. Probiotics can fighters at any circumstance with harmful microorganisms and maintain/ colonize human digestive system. 3. Probiotics helps in breaking of food into much smaller Recent Application of Probiotics in Food and Agricultural Science 5 The most common probiotics are Lactobacillus and Bifidobacterium.In general most probiotics are gram-positive, usually catalase-negative, rods with rounded ends, and occur in pairs, short, or long chains [7]. They are non-flagellated, non-motile and non-spore-forming, and are intolerant to salt. Practical Applications of Probiotics in Health and Disease 4 functions, including protective functions, structural functions, and metabolic functions. The protective functions have also been referred to as colonization resistance since properly colonized animals are more resistant to infection. When poultry meat and eggs were recognised as a vehicle for human salmonella, the application of probiotics as a tool for preventing this disease was actively explored. Cox and Pavic, (Reference COX and PAVIC 2009) reported that increased numbers of Lactobacillus and Bifadobacterium spp. correlated with reduced Salmonella spp. prevalence. The potential application of probiotics and prebiotics for the prevention and treatment of COVID-19 NPJ Sci Food. 2020 Oct 5;4:17. doi: 10.1038 Probiotics consist of single or mixed cultures of live microorganisms that can beneficially affect the host by maintaining the intestinal or lung microbiota that play a major role in human health Probiotics: potential pharmaceutical applications Realisation of the importance of human gut microbiota in health restoration and maintenance has kindled an interest in probiotics. Probiotics are defined as the microbial food supplements, which beneficially affect the host by improving its intestinal microbial balance. drug delivery systems including probiotics, focusing on their development, various applications, and benefits. The paper provides evidence in support of research studying the use of biopolymers in the development of new drug delivery systems, explores the challenges and limitations in in- Probiotics are living micro-organisms or bacteria that we consume in foods or beverages. Probiotic bacteria are friendly bacteria that Symposium: Clinical Applications of Probiotics in Human Health. September 14-15, 2007, Las Vegas, Nevada. The Pe

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